Oral Pathology .
Courses Offered:
BDS: Oral Histology and Dental Anatomy
Oral Pathology
MDS: Started in 1984.
Three-year course.
Total number of seats are 3 per year.
PhD: In Oral Pathology
Guide- Dr. R Rajendran.
University of Kerala.
Number of candidates registered for PhD - 3
DEPARTMENT OF ORAL PATHOLOGY AND MICROBIOLOGY:
One of the seniormost departments of its kind in this country, running courses for the undergraduate, postgraduate and National Board Examinations in the specialty of Oral Pathology and Microbiology. The department is also recognized as an approved center for PhD research training under the University of Kerala. Elevated to the senior level by the induction of postgraduate course of MDS in 1984 and annually admits three candidates for the course, one of them from the national quota. The National Board of Examinations has recognized this department as one of their Dip.NB training and examination centers. The department is having an excellent research background in the field of oral diseases in general and oral cancer in particular. The first overseas research collaboration in the field of oral cancer in this country was initiated in this department in 1965 with DANIDA assistantship under the supervision of Late Prof J.J. Pindborg and Late Prof Jacob Zechariah. The research tradition is still continuing and the incumbent Professor Dr. R. Rajendran was awarded with a PhD for the first time in the dental faculty for his submitted thesis on oral submucous fibrosis. This PhD is credited as the first PhD in the specialty offered by any of the Indian universities. The department has established research collaborations with many centers in India and abroad which includes reputed institutes like The National Institutes of Health (NIH), Bethesda, USA. Many research papers have been published on various aspects of oral diseases in both national and international journals. For more information kindly visit our website www.teleoralpathology.com
RESEARCH PROJECTS
1. Co- investigator
Project on oral submucous fibrosis (OSMF): Sanctioned and financed by the State Committee on Science, Technology and Environment (STEC)- Government of Kerala.
1984-85- Completed Project
2. Principal Investigator
Project on OSMF- Sanctioned and financed by STEC- 1987-88 – Completed. G.O. No. 185/87/ PIG. Dt. 17.02.1987
3. Principal Investigator
Project on oral pre cancer and cancer : Sanctioned and financed by STEC- 1988-89 completed.
G.O. M.S. No. 21/88 STEC dated. 06.04.1988
4. Principal Investigator
Project on OSMF : Sanctioned and financed by the Department of Science and Technology, Govt. of India, New Delhi.
G.O. No. REF/ SP/ YS/ L72/ 87 dated. May 31st 1988- Completed Project
ONGOING RESEARCH PROJECTS
1.Tracing disease gene(s) in non-syndromic clefts of orofacial region – an analysis
into the nature of the genetic defect.
2. Genetic profiling of a cohort of areca- nut associated oral submucous fibrosis: An
analysis of their HLA haplotyping and TGF beta 1 polymorphism.
3. Role of nitric oxide synthase as angiogenic modifier in oral submucous fibrosis.
Familial occurrence of oral submucous fibrosis: A population based survey.
Stromal collagenization is site specific in oral submucous fibrosis: A histochemical analysis using collagen specific special stains.
Characterization and quantification of mucosal vasculature in oral submucous fibrosis.
(All the above cited research projects are ongoing and is at different stages of completion.)
II. Name of Principal and Co-investigator
DR. R. RAJENDRAN, Ph.D
Professor and Head
Dept of Oral Pathology and Microbiology (PI)
DR MOINAK BANERJEE
Scientist
Rajiv Gandhi Center for Biotechnology
Poojapura
Trivandrum. (CI)
Duration of the project – 3 years
Funding source – DST and STEC, Govt of Kerala.
Fund requested – Rs 500,000. (Five lakhs)
Ethical committee clearance – Received
Order no:………….
Details of projects undertaken for the last three years.
Further on the causation of oral submucous fibrosis
Ind. J Dent Res 2002;13: 74-81.
Desmoplastic amelobloma – A case report
J. Oral. Max Facial Surg. 2002;60:1186-88
3. Intestinal parasites and anaemic status in oral submucous fibrosis
J Int Med Sci Aca 2005; 18 (2): 73-74.
4. Malignant melanoma of the oral cavity: Report of two cases with a brief
review of literature. ( In Press )
5. Liver ultrasound and faecal copper estimation in oral submucous
fibrosis.
Ind J Dent Res 2003;14:13-21.
6. Angiolymphoid hyperplasia with eosinophilia(ALHE): A case report
J Oral Max Fac Path 2005
7. Morphohistometric analysis of advancing tumor fronts in malignancies
associated with oral submucous fibrosis.
Indian Journal of Dental Research 2003; 14 (4): 194 – 205.
8. Microarrays: An advance in laboratory practice.
Proceedings of the XIIIth National Conference of Indian Association of
Oral & Maxillofacial Pathologists – 19th – 21st November 2004 – Calicut,
India. pp. 26 – 39.
9. Oral Lichen planus.
Journal of Indian Dental Association (Central Kerala Br)
2004; 13(5): 6 – 15.
10. Oral Leukoplakia (leukokeratosis): compilation of facts and
figures.
J Oral Max Fac Path 2004; 8 (2): 58 – 68.
11. Cell death does not herald epithelial involution (“atrophy”) in oral
submucous fibrosis : a TEM study.
Ind J Dent Res 2004; 15 (1): 13 – 19.
12. Familial occurrence of oral submucous fibrosis: report of 8 families from
Northern Kerala, South India.
Ind J Dent Res 2004: 15(4): 139 – 144.
Characterization and quantification of mucosal vasculature in oral
submucous fibrosis. (In Press)
Plexiform neurofibroma of the gingiva: report of a case (In press)
Undifferentiated carcinoma of the submandibular salivary gland with
fulminant clinical behavior: report of a case. (In Press)
Oral Lichen Planus- Review.
J Oral Max Fac Pathol 2005; 9 : 3 –5.
Pentoxifyllin (Trental) as a therapeutic agent in early oral submucous fibrosis:
A pilot clinical trial. (In Press)
RESEARCH COLLABORATIONS WITH:
Regional Cancer Centre
Medical College Campus.
Trivandrum.
Rajeev Gandhi Institute of Biotechnology.
Poojjapura
Trivandrum.
NIDCR, National Institutes Of Health
Bethesda, United States.
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